000			02797nam a22002655i 4500
005			20210812160316.0
008			121227s1990 xxu| s |||| 0|eng d
020			_a9781461397977 _9978-1-4613-9797-7
050		4	_aQD415-436
082	0	4	_a547 _223
100	1		_aCarey, Francis A. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
245	1	0	_aAdvanced Organic Chemistry _h[electronic resource] : _bPart B: Reactions and Synthesis / _cby Francis A. Carey, Richard J. Sundberg.
250			_a3rd ed. 1990.
264		1	_aNew York, NY : _bSpringer US : _bImprint: Springer, _c1990.
300			_aLVI, 799 p. 3 illus. _bonline resource.
490	1		_aPart B: Reactions and Synthesis
520			_aThe main theme of Part B is the description of synthetically useful reactions and the illustration of their application. We have attempted to update the material to reflect the most important advances in synthetic methodology. Because of the extensive developments in the use of organic derivatives of transition metals, as well as of silicon and tin, we have separated the organometallic material into three chapters. Chapter 7 emphasizes organolithium and organomagnesium chemistry and also considers the group lIB metals. Transition metal chemistry is discussed in Chapter 8, with emphasis on copper and palladium intermediates. In Chapter 9, the carbon-carbon bond-forming reactions of organoboranes, silanes, and stannanes are discussed. The increased importance of free-radical reactions in synthesis has led to the incorporation of a section on radical reactions into Chapter 10, in which carbocations, carbenes, and nitrenes are also discussed. Certainly a major advance in synthetic chemistry during the 1980s was the development of methods for enantioselective synthesis. We have increased the level of attention to stereochemistry in the discussion of many reactions. In areas in which new stereoselective methods have been well developed, such as in aldol condensa­ tions, hydroboration, catalytic reduction, and epoxidation, we discuss these methods. The final chapter discusses some of the general issues which must be addressed in multistep synthesis and provides some illustrative syntheses which can provide the basis for more detailed study of this aspect of synthetic chemistry.
650		0	_aOrganic chemistry.
650		0	_aMedicinal chemistry.
650	1	4	_aOrganic Chemistry. _0https://scigraph.springernature.com/ontologies/product-market-codes/C19007
650	2	4	_aMedicinal Chemistry. _0https://scigraph.springernature.com/ontologies/product-market-codes/C28000
700	1		_aSundberg, Richard J. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
710	2		_aSpringerLink (Online service)
773	0		_tSpringer Nature eBook
856	4	0	_uhttps://doi.org/10.1007/978-1-4613-9797-7
999			_c1458 _d1458