000			01890nam a2200289Ia 4500
003			OSt
005			20240210123436.0
008			231229s9999 xx 000 0 und d
020			_a9780195182187
040			_cIISER BPR
041			_aEng
082			_a570.28 _2FRA _b23rd
100			_aFrank, Joachim
245		0	_aThree-dimensional electron microscopy of macromolecular assemblies : _bVisualization of biological molecules in their native state
250			_a2nd ed.
260			_aNew York: _bOUP, _cc2006.
300			_axv, 410p. : _bill, pbk. ; _c22cm.
520			_aCryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics and structural biology at present, and Frank is arguably the most distinguished practitioner of this art. CryoEM is likely over the next few years to take over much of the structural approaches currently requiring X-ray crystallography, because one can now get good and finely detailed images of single molecules down to as little as 200,000 MW, covering a substantial share of the molecules of greatest biomedical research interest. This book, the successor to an earlier work published in 1996 with Academic Press, is a natural companion work to our forthcoming book on electron crystallography by Robert Glaeser, with contributions by six others, including Frank. A growing number of workers will employ CryoEM for structural studies in their own research, and a large proportion of biomedical researchers will have a growing interest in understanding what the capabilities and limits of this approach are. Includes illustrations, figures, tables, appendices, references and index.
650			_aLife sciences
650			_aBiology
650			_aAuxiliary Technique & Procedure
650			_aElectron Microscopy
942			_cBK _2ddc
942			_2ddc
947			_a15404.949999999999
948			_a22
999			_c3257 _d3257