000			03339nam a2200325Ia 4500
003			OSt
005			20240827111349.0
008			240709s9999 xx 000 0 und d
020			_a9781847551108
040			_cIISER-BPR
041			_aENG
082			_a546.415 _bPRO _223rd
100			_aProcter, David J.
222			_aChemistry
245		0	_aOrganic synthesis using Samarium Diiodode : _bA practical Guide
250			_a1st ed.
260			_aCambridge: _bRSC Publishing, _cc2010.
300			_axvi, 204p. : _bill, hbk. ; _c24cm
520			_aSamarium diiodide is one of the most important reducing agents available to synthetic organic chemists. The lanthanide(II) reagent acts by single-electron transfer to organic substrates leading to the formation of both radical and/or anionic intermediates. The power of the reagent arises from its versatility - samarium diiodide can be used in processes ranging from functional group conversions to elaborate carbon-carbon bond-forming cyclization sequences that result in a dramatic increase in molecular complexity. In addition, reactions involving samarium diiodide often show high stereoselectivity as samarium ions can coordinate to Lewis basic sites on substrates and can direct the stereochemical course of reactions. The ability to fine-tune the reactivity of the reagent by the use of additives and co-solvents is an additional, attractive feature. Although samarium diiodide is used extensively by organic chemists, there is still a widely held view that the reagent can be difficult to prepare and use. In addition, samarium diiodide can mediate such a wide variety of organic chemistry that potential new users are often overawed by the extensive primary literature on the reagent. The objective of this book is to provide a concise, practical guide to the reagent. Rather than being a comprehensive review of the chemistry of samarium diiodide, this user-friendly book adopts an "an all you need to know" approach to the topic. The international authors are well-known for their work with the reagent and their expertise covers current developments in new reactivity and selectivity, applications in target synthesis, co-solvent and additive effects, coordination chemistry and mechanism. The book includes the best methods for preparing and handling the reagent, how solvents, co-solvents and additives alter reactivity, the basic mechanisms of reactions, common transformations using the reagent, and emerging areas in samarium diiodide chemistry. The authors have distilled the extensive primary literature to allow the reader to quickly grasp an understanding of the reagent and its utility. The illustrative practical procedures help the reader to prepare and use the reagent in the laboratory while references from the recent literature allow readers to pursue their interest in the popular reagent. The book also contains many illustrations and chemical schemes. Also includes illustrations, bibliographic references and subject index.
650			_aInorganic Chemistry
650			_aSamarium and Europium
650			_aOrganic Synthesis
650			_aOrganic Synthesis Using Samarium Diiodide
700			_aFlowers II, Robert A.
700			_aSkrydstrup, Troels
942			_cBK _2ddc
942			_2ddc
947			_a9776.3708
948			_a0.22
999			_c4158 _d4158