000 02323nam a2200349Ia 4500
003 OSt
005 20250217163853.0
008 240709s9999 xx 000 0 und d
020 _a9781782620648 (hbk.)
_c£ 179.00
040 _bENG
_cIISER-BPR
041 _aENG
082 _a615.9253
_bCRI
_223rd
100 _aCrichton, Robert
_4Ed.
_93104
222 _aChemistry
245 0 _aMetal chelation in medicine
250 _a1st ed.
260 _aCambridge:
_bRSC Publishing,
_cc2017.
300 _axiii, 322p. :
_bill(some col.). ;
_c24cm
440 _aRSC Metallobiology Series
_vNo. 8
_93105
504 _aIncludes illustrations (some colour), abbreviations, acknowledgements, bibliographic references and subject index.
520 _aMetal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.
650 _aPharmacology and Therapeutics
_93106
650 _aToxicology
_93107
650 _aInorganic Poisoning
_93108
650 _aMetal Poisoning
_93109
700 _aWard, Roberta
_4Ed.
_93110
700 _aHider, Robert
_4ed.
_93111
942 _cBK
_2ddc
942 _2ddc
947 _a18422.68
948 _a0.22
999 _c4163
_d4163