000			02249nam a2200337Ia 4500
003			OSt
005			20240822121044.0
008			240709s9999 xx 000 0 und d
020			_a9781782620648
040			_cIISER-BPR
041			_aENG
082			_a615.9253 _bCRI _223rd
100			_aCrichton, Robert _4Ed.
222			_aChemistry
245		0	_aMetal chelation in medicine
250			_a1st ed.
260			_aCambridge: _bRSC Publishing, _cc2017.
300			_axiii, 322p. : _bill(some col.), hbk. ; _c24cm
440			_aRSC Metallobiology Series _vNo. 8
520			_aMetal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques. Also includes illustrations (some colour), abbreviations, acknowledgements, bibliographic references and subject index.
650			_aPharmacology and Therapeutics
650			_aToxicology
650			_aInorganic Poisoning
650			_aMetal Poisoning
700			_aWard, Roberta _4Ed.
700			_aHider, Robert _4ed.
942			_cBK _2ddc
942			_2ddc
947			_a18422.68
948			_a0.22
999			_c4163 _d4163